Edexcel IAL Biology Notes for 2025 - 2026 Exams

Hosni Showike • 19 September 2024

Topic 1: Biological Molecules

ial biology notes biological molecules

1.1 Dipole Nature

The water molecule has unique properties, making it play essential roles in all organisms.

The shared electrons in the water molecule are quite closer to the oxygen atom than the two hydrogen atoms. As a result, the oxygen becomes slightly (partially) negative, while the two hydrogens become slightly positive. These opposite partial charges on each side of the water molecule turn the water molecule into a dipole. Dipole: refers to the separation of opposite charges within the water molecule.

1.2 Hydrogen Bonds

Water molecules are attracted to each other due to their dipolar nature. The partially negative (δ-) oxygen atom in one water molecule is attracted to a partially positive (δ+) hydrogen atom in a neighbouring water molecule. These attractions are known as hydrogen bonds. Hydrogen bonds are weak attraction forces; however, they do affect the properties of different molecules. Other than water molecules, hydrogen bonds do also exist in DNA, proteins, starch and many other molecules. Hydrogen bonds must include hydrogen atoms (δ+) attracted to either oxygen or nitrogen atoms in another molecule. The reason why hydrogen bonds only exist between these specific atoms is that both nitrogen and oxygen atoms tend to be slightly negative (δ-), and they get attracted very well to the slightly positive hydrogen atoms.

1.3 Importance Of Water In Transport

The dipolar nature of water and its ability to form hydrogen bonds explain all the unique properties of water:

a. Water is the transport medium in all organisms (such as blood), and this can be attributed to these properties:

  1. Water is a good solvent for charged (like salts) and polar molecules (like glucose).
  2. Water is a liquid over a large temperature range which can be explained by two characteristics:
  • i. Water has a high latent heat of evaporation: a large amount of heat energy is needed for water molecules to turn from the liquid state to the gas state.
  • ii. Water has a high specific heat capacity: lots of heat energy is needed to raise the temperature of the water. This means that the temperature in water remains relatively stable despite the significant changes in the temperature of the surrounding environment.

Water assists the mass flow of fluids: mass flow is the movement of fluids in one direction down a pressure gradient (from high to low pressure). The circulation of blood is a good example of mass flow. Two essential properties of water help mass flow happen:

  • i. Water is cohesive: water molecules stick to each other due to hydrogen bonds.
  • ii. Water is adhesive: hydrogen bonds allow water to get attracted to the vessels where it is flowing through.

1.4 Solubility In Water

Polar molecules can be either fully charged like ionic compounds (salts) or partially charged like sugars.

Polar molecules dissolve well in water because water surrounds these molecules and forms bonds with them. Non-polar molecules are usually hydrocarbons (made up of carbon and hydrogen only). They are described as being hydrophobic. Hydrocarbons do not dissolve in water because they cannot form bonds with it.

Size also plays an essential role in solubility; smaller molecules are more likely to dissolve than larger ones.

Try a free Class

IGCSE and IAL Guide for 2025 - 2026 Exams

IGCSE to A-Level Chemistry mind map showing the expanded content.
by Hosni Showike 11 July 2026
Bridge the gap between IGCSE and A-Level Chemistry with an examiner's plan: what to carry forward, why the mole decides your grade, and the 40-day exam rule.
Student climbing from IGCSE to A-Level Biology and Chemistry.
by Hosni Showike 3 July 2026
Is A-Level harder than IGCSE? See what really changes in Biology and Chemistry, why IGCSE is your foundation, and how to close the gap — from an examiner.
A-level Biology versus Chemistry difficulty comparison illustration.
by Hosni Showike 27 June 2026
Which A-level is harder, chemistry or biology? Compare 2025 grade data, Ofqual grading-severity research and an examiner's marking insight to choose with confidence.
IGCSE Chemistry 0620 grade boundary forecast graph, Variant 1 versus Variant 2.
by Hosni Showike 19 June 2026
See what the June 2026 IGCSE Chemistry (0620) grade boundaries could look like, with five years of real Variant 1 and Variant 2 thresholds and an examiner's forecast.
 IGCSE Biology 0610 A* grade boundary trend with an 87% target mark.
by Hosni Showike 12 June 2026
Wondering about IGCSE Biology grade boundaries for June 2026? See the five-year 0610 A* trend, why Variant 2 is toughest, and the safe 87% mark to target.
Student revising Edexcel IAL Biology with past papers, notes, and a laptop showing a graph
by Hosni Showike 1 June 2026
Is Biology one of the hardest A Levels? Find out how Edexcel IAL Biology difficulty works by unit, what marks you need, and how to close the gap in your exams.
Student studying Biology notes at a desk with two open textbooks of different difficulty levels
by Hosni Showike 29 May 2026
The IGCSE to A-Level jump is a shift in thinking, not just content. Learn what changes, how to study differently, and how to choose the right AS subject for your goals.
Teenage student solving a chemistry multiple-choice exam at a clean desk with periodic table
by Hosni Showike 27 May 2026
Score 36+ on IGCSE Chemistry Paper 2 with a proven 4-stage past paper method. Includes diagnostic test, error logging, and timed mock strategy from an expert teacher.
A focused student in a dark blue sweater sits at a rustic wooden desk, circling MCQs on paper
by Hosni Showike 22 May 2026
Master IGCSE Biology and Chemistry Paper 2 with 10 proven MCQ techniques. Process of elimination, command lines, extreme words, and the examiner mindset explained.
Edexcel IAL Biology Unit 5 exam prediction thumbnail with exam paper and teacher portrait.
by Hosni Showike 13 May 2026
Claim every free mark on Edexcel IAL Biology Unit 5 WBI15. Your final-week strategy for the scientific article, practicals, and definitions in June 2026.
Show More