IGCSE Biology 

2026 - 2028

Syllabus Checklist

IGCSE Biology – Gas Exchange in Humans

Topic 11: Gas Exchange in Humans

Gas Exchange in Humans

Describe the features of gas exchange surfaces in humans, limited to: ▪ Large surface area ▪ Thin surface ▪ Good blood supply ▪ Good ventilation with air.
Identify in diagrams and images the following parts of the breathing system : lungs, diaphragm, ribs, intercostal muscles, larynx, trachea, bronchi, bronchioles, alveoli, and associated capillaries.
Investigate the differences in composition between inspired and expired air using limewater as a test for carbon dioxide .
Describe the differences in composition between inspired and expired air , limited to: oxygen, carbon dioxide, and water vapour.
Investigate and describe the effects of physical activity on the rate and depth of breathing .
Explain the differences in composition between inspired and expired air.
Explain the link between physical activity and the rate and depth of breathing in terms of: ▪ Increased carbon dioxide concentration in the blood ▪ Detection by the brain ▪ Increased rate and depth of breathing.
Explain the role of goblet cells , mucus , and ciliated cells in protecting the breathing system from pathogens and particles.