IGCSE Biology 

2026 - 2028

Syllabus Checklist

IGCSE Biology – Respiration

Topic 12: Respiration

1 Respiration

State the uses of energy in living organisms, including: muscle contraction, protein synthesis, cell division, active transport, growth, passage of nerve impulses, and maintaining a constant body temperature.
Investigate and describe the effect of temperature on respiration in yeast.

2 Aerobic Respiration

Describe aerobic respiration as the chemical reactions in cells that use oxygen to break down nutrient molecules to release energy.
State the word equation for aerobic respiration as: glucose + oxygen → carbon dioxide + water.
State the balanced chemical equation for aerobic respiration as: C₆H₁₂O₆ + 6O₂ → 6CO₂ + 6H₂O.

3 Anaerobic Respiration

Describe anaerobic respiration as the chemical reactions in cells that break down nutrient molecules to release energy without using oxygen.
State that anaerobic respiration releases much less energy per glucose molecule than aerobic respiration.
State the word equation for anaerobic respiration in yeast as: glucose → alcohol + carbon dioxide.
State the word equation for anaerobic respiration in muscles during vigorous exercise as: glucose → lactic acid.
State the balanced chemical equation for anaerobic respiration in yeast as: C₆H₁₂O₆ → 2C₂H₅OH + 2CO₂.
State that lactic acid builds up in muscles and blood during vigorous exercise, causing an oxygen debt .
Outline how the oxygen debt is removed after exercise, limited to: ▪ Continued fast heart rate transports lactic acid in the blood from the muscles to the liver. ▪ Continued deeper and faster breathing supplies oxygen for aerobic respiration of lactic acid. ▪ Aerobic respiration of lactic acid in the liver.